Английская Википедия:Dienestrol
Шаблон:Short description Шаблон:Drugbox Dienestrol (Шаблон:Abbrlink, Шаблон:Abbrlink) (brand names Dienoestrol, Denestrolin, Dienol and many othersШаблон:Efn), also known as dienoestrol (Шаблон:Abbrlink), is a synthetic nonsteroidal estrogen medication of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe.[1][2][3][4] It has been studied for use by rectal administration in the treatment of prostate cancer in men as well.[5] The medication was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.[4] Dienestrol is a close analogue of diethylstilbestrol.[6] It has approximately 223% and 404% of the affinity of estradiol at the ERα and ERβ, respectively.[7]
Dienestrol diacetate (brand names Faragynol, Gynocyrol, others) also exists and has been used medically.[2]
Isomers
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Dienestrol (unspecified) - CAS 84-17-3
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E,E-Dienestrol - CAS 13029-44-2
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Z,Z-Dienestrol - CAS 35495-11-5
See also
Notes
References
Шаблон:Estrogens and antiestrogens
Шаблон:Estrogen receptor modulators
Шаблон:Genito-urinary-drug-stub
