Английская Википедия:Diethylstilbestrol dipalmitate

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Diethylstilbestrol dipalmitate (brand names Palmestril, Stilpalmitate), also known as stilpalmitate, is a synthetic, nonsteroidal estrogen of the stilbestrol group and an ester of diethylstilbestrol (DES) that was formerly marketed but is now no longer available.[1][2] Its actions and uses are essentially the same as those of DES, but it is absorbed more slowly and for this reason has a much longer duration of action and improved tolerability in comparison.[3] A single 5 mg intramuscular injection of DES dipalmitate in oil solution has been found to have an average duration of action of 8 to 10 weeks[4] in terms of relief of menopausal symptoms, with a duration of as long as 15 to 16 weeks occurring in some women.[5][6][7] A single 15 or 20 mg intramuscular injection of DES dipalmitate in oil solution will control menopausal symptoms for 3 months or longer.[8] DES dipalmitate in aqueous suspension by intramuscular injection has been studied as well.[9]

See also

References

Шаблон:Reflist

Шаблон:Estrogens and antiestrogens Шаблон:Estrogen receptor modulators

Шаблон:Genito-urinary-drug-stub