Английская Википедия:Dihydrouracil dehydrogenase (NAD+)

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Шаблон:Short description Шаблон:Infobox enzyme

In enzymology, a dihydrouracil dehydrogenase (NAD+) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

5,6-dihydrouracil + NAD+ <math>\rightleftharpoons</math> uracil + NADH + H+

Thus, the two substrates of this enzyme are 5,6-dihydrouracil and NAD+, whereas its 3 products are uracil, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5,6-dihydrouracil:NAD+ oxidoreductase. Other names in common use include dehydrogenase, dihydrouracil, dihydropyrimidine dehydrogenase, dihydrothymine dehydrogenase, pyrimidine reductase, thymine reductase, uracil reductase, and dihydrouracil dehydrogenase (NAD+). This enzyme participates in 3 metabolic pathways: pyrimidine metabolism, beta-alanine metabolism, and pantothenate and coa biosynthesis.

References

Шаблон:Reflist

Шаблон:CH-CH oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.3-enzyme-stub