Английская Википедия:Donitriptan

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Шаблон:Short description Шаблон:Drugbox

Donitriptan (INN) (code name F-11356) is a triptan drug which was investigated as an antimigraine agent but ultimately was never marketed.[1] It acts as a high-affinity, high-efficacy/near-full agonist of the 5-HT1B (pKi = 9.4–10.1; IA = 94%) and 5-HT1D receptors (pKi = 9.3–10.2; IA = 97%), and is among the most potent of the triptan series of drugs.[2][3][4] Donitriptan was being developed in France by bioMérieux-Pierre Fabre and made it to phase II clinical trials in Europe before development was discontinued.[5][6][7]

References

Шаблон:Reflist

Шаблон:Antimigraine preparations Шаблон:Serotonergics Шаблон:Piperazines


Шаблон:Analgesic-stub