Английская Википедия:Ductus venosus

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Шаблон:Short description Шаблон:Infobox vein In the fetus, the ductus venosus (Arantius' duct after Julius Caesar Aranzi[1]) shunts a portion of umbilical vein blood flow directly to the inferior vena cava.[2] Thus, it allows oxygenated blood from the placenta to bypass the liver. Compared to the 50% shunting of umbilical blood through the ductus venosus found in animal experiments, the degree of shunting in the human fetus under physiological conditions is considerably less, 30% at 20 weeks, which decreases to 18% at 32 weeks, suggesting a higher priority of the fetal liver than previously realized.[3] In conjunction with the other fetal shunts, the foramen ovale and ductus arteriosus, it plays a critical role in preferentially shunting oxygenated blood to the fetal brain. It is a part of fetal circulation.

Anatomic course

The pathway of fetal umbilical venous flow is umbilical vein to left portal vein to ductus venosus to inferior vena cava and eventually the right atrium. This anatomic course is important in the assessment of neonatal umbilical venous catheterization, as failure to cannulate through the ductus venosus results in malpositioned hepatic catheterization via the left or right portal veins. Complications of such positioning can include hepatic hematoma or abscess.

Postnatal closure

The ductus venosus is open at the time of birth and that is the reason why umbilical vein catheterization works. The ductus venosus naturally closes during the first week of life in most full-term neonates; however, it may take much longer to close in pre-term neonates. Functional closure occurs within minutes of birth. Structural closure in term babies occurs within 3 to 7 days.

After it closes, the remnant is known as ligamentum venosum.

Шаблон:Anchor If the ductus venosus fails to occlude after birth, it remains patent (open), and the individual is said to have a patent ductus venosus and thus an intrahepatic portosystemic shunt (PSS).[4] This condition is hereditary in some dog breeds (e.g. Irish Wolfhound). The ductus venosus shows a delayed closure in preterm infants, with no significant correlation to the closure of the ductus arteriosus or the condition of the infant.[5] Possibly, increased levels of dilating prostaglandins leads to a delayed occlusion of the vessel.[5]

Файл:Agenesis of ductus venosus human.jpg
Agenesis of ductus venosus (ADV) in a first trimester case with umbilical vein drainage into inferior vena cava (IVC) and increased nuchal translucency. (A): Transverse plane of the FT fetal abdomen, with high-definition directional power Doppler applied. An ”H”-shaped variant of the intrahepatic portal veins connection is identified; (B): high-definition directional power Doppler in the sagittal plane of the fetal abdomen (same case) showing ADV with umbilical vein drainage into the inferior vena cava; (C): mid-sagittal view of the fetal face with the measurement of the thickened NT. MPV main portal vein, St stomach, LPV left portal vein, UV umbilical vein, RPVa anterior branch of right portal vein, RPVp posterior branch of right portal vein, Ao aorta, IVC inferior vena cava, ADV ductus venosus agenesis, P palate, NB nasal bone, NT nuchal translucency.

References

Шаблон:Reflist

Шаблон:Development of circulatory system Шаблон:Veins