Английская Википедия:Duret haemorrhages

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Шаблон:Infobox medical condition (new) Duret haemorrhages are small linear areas of bleeding in the midbrain and upper pons of the brainstem. They are caused by a traumatic downward displacement of the brainstem.[1]

They are named after Henri Duret.

Causes

Duret haemorrhages are named after Henri Duret,[2] who discovered these brainstem lesions in dogs with increased intracranial pressure.[3] They are small linear areas of bleeding in the midbrain and upper pons of the brainstem.Шаблон:Cn

They are caused by a traumatic downward displacement of the brainstem with parahippocampal gyrus herniation through the tentorial notch.[4] or acute hematoma, edema following trauma, abscess, or tumor.Шаблон:Citation needed

Pathogenesis

Duret haemorrhages are haemorrhages secondary to raised intracranial pressure with formation of a transtentorial pressure cone involving the front part of the cerebral peduncles, the cerebral crura. Increased pressure above the tentorium may also involve other midbrain structures.Шаблон:Citation needed

Kernohan's notch is a groove in the cerebral peduncle which may be caused by this displacement of the brainstem against the tentorial incisure. The resulting ipsilateral hemiparesis is a false localising sign,[5] known as the Kernohan-Woltman syndrome.[6] This may succeed or accompany temporal lobe (uncal) herniation and subfalcian herniation secondary to a supratentorial mass.Шаблон:Cn

The pathophysiological mechanism is uncertain[7] but is probably caused by the displacement of the brainstem stretching and tearing perforating branches of the basilar artery to the pons; venous infarction may play a role.Шаблон:Citation needed

Diagnosis

Duret haemorrhages can be demonstrated by medical imaging techniques of CT or MRI though difficult.[8]

Prognosis

Duret haemorrhages usually indicate a fatal outcome.[9] However, survival has been reported.[10][11]

Society and culture

George Gershwin died after emergency surgery of a large brain tumour, believed to have been a glioblastoma. The fact that he had suddenly collapsed and become comatose when he stood up on his last day of life, has been interpreted as brain herniation and Duret haemorrhages.[12]

References

Шаблон:Reflist

External links

Шаблон:Cerebrovascular diseases

  1. Шаблон:Cite book
  2. Шаблон:Cite journal
  3. Duret haemorrhage - Neurosurgical lexicon
  4. Шаблон:Cite book
  5. Collier, J. The false localizing signs of intracranial tumour. Brain 27:490-508, 1904.
  6. J. W. Kernohan JW, Woltman HW. Incisura of the crus due to contralateral brain tumor. Archives of Neurology and Psychiatry, Chicago, 1929, 21: 274–287.
  7. Шаблон:Cite journal
  8. Шаблон:Cite journal
  9. Шаблон:Cite journal
  10. Шаблон:Cite journal
  11. Шаблон:Cite journal
  12. Takahiro Mezaki, Gershwin's death and Duret haemorrhage NEJM, 12 August 2017