Английская Википедия:Echinochrome A

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Echinochrome A, 7-ethyl-2,3,5,6,8-pentahydroxy-1,4-naphthoquinone is a polyhydroxylated 1,4-naphthoquinone,[1] a type of pigments commonly found in sea urchin shell ("test"), spine, gonads, coelomic fluid, and eggs, of sea urchin.[2] These type of pigments are commonly known as spinochromes and are natural marine phenolic compounds with known and various clinical effects and modes of action.[3]

First extracted from the sea urchin Scaphechinus mirabilis, it is the active substance of histochrome and Echino-A. Histochrome is used for ophthalmic diseases and Ischemic heart disease. Echino-A has been used in nutraceutical form to diminish glucose levels, cholesterol and tryglicerides. The unique properties and the absence of adverse effects of Echinochrome A as a potent antioxidant has made it the focus of intense scientific and clinical studied for more than 30 years.[4][5][6] The several hydroxyl groups have the ability to diminish reactive oxygen species (ROS) in the cells, preventing redox imbalance. Echinochrome A has been found to target ophtalmologic, cardiovascular, cerebrovascular, inflammatory and metabolic diseases through its biological functions by targeting specific molecular signals. The regulation effects produced by echinochrome A in the cells makes this molecule a candidate to improve health.[6][7] Sea urchins are known for their health properties for centuries, for example in the "Materia medica" of the Ming Dynasty authored by Li Zhongli in 1647.[8]

References

Шаблон:Reflist

  1. National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 135457951, Echinochrome A. Retrieved April 13, 2022 from https://pubchem.ncbi.nlm.nih.gov/co
  2. Шаблон:Cite journal
  3. Шаблон:Cite journal
  4. Шаблон:Cite journal
  5. Шаблон:Cite journal
  6. 6,0 6,1 Шаблон:Cite journal
  7. Шаблон:Cite journal
  8. Шаблон:Cite journal This content is a preprint and has not been peer-reviewed