Английская Википедия:Ectopic hormone

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Шаблон:Short description

An ectopic hormone is a hormone produced by tumors derived from tissue that is not typically associated with its production.[1]

On the other hand, the term entopic is used to refer to hormones produced by tissue in tumors that are normally engaged in the production of that hormone. [2]

The excess hormone secretion is considered detrimental to the normal body homeostasis.[3] This hormone production typically results in a set of signs and symptoms that are called a paraneoplastic syndrome.[2]

Some clinical syndromes caused by ectopic hormone production include:

Syndrome Main causal cancers Ectopic hormone
Cushing syndrome Ectopic ACTH and ACTH-like substance
Syndrome of inappropriate antidiuretic hormone Ectopic Antidiuretic hormone[4]
Hypercalcemia Ectopic PTHrP (Parathyroid hormone-related protein), TGF-α, TNF, IL-1[4]
Hypoglycemia Ectopic Insulin-like growth factor 2
Hyperaldosteronism Ectopic Aldosterone[6]

References

Шаблон:Reflist