Английская Википедия:Edgewood Arsenal human experiments
Шаблон:Short description Шаблон:Hatnote
From 1948 to 1975, the U.S. Army Chemical Corps conducted classified human subject research at the Edgewood Arsenal facility in Maryland. The purpose was to evaluate the impact of low-dose chemical warfare agents on military personnel and to test protective clothing, pharmaceuticals, and vaccines. A small portion of these studies were directed at psychochemical warfare and grouped under the prosaic title of the "Medical Research Volunteer Program" (1956–1975). The MRVP was also driven by intelligence requirements and the need for new and more effective interrogation techniques.
Overall, about 7,000 soldiers took part in these experiments that involved exposures to more than 250 different chemicals, according to the Department of Defense (DoD). Some of the volunteers exhibited symptoms at the time of exposure to these agents but long-term follow-up was not planned as part of the DoD studies.[1] The experiments were abruptly terminated by the Army in late 1975 amidst an atmosphere of scandal and recrimination as lawmakers accused researchers of questionable ethics. Many official government reports and civilian lawsuits followed in the wake of the controversy.
The chemical agents tested on volunteers included chemical warfare agents and other related agents:[1]
- Anticholinesterase nerve agents (VX, sarin) and common organophosphorus (OP) and carbamate pesticides
- Mustard agents
- Nerve agent antidotes including atropine and scopolamine
- Nerve agent reactivators, e.g. the common OP antidote 2-PAM chloride
- Psychoactive agents including LSD, PCP, cannabinoids, and BZ
- Irritants and riot control agents
- Alcohol and caffeine
History
Background and rationale
After World War II, U.S. military researchers obtained formulas for the three nerve gases developed by the Nazis—tabun, soman, and sarin—and conducted studies on them at the US Army Edgewood Chemical Biological Center. These studies included a secret human subjects component at least as early as 1948, when "psychological reactions" were documented in Edgewood technicians. Initially, such studies focused solely on the lethality of the gases and its treatment and prevention. A classified report entitled "Psychochemical Warfare: A New Concept of War" was produced in 1949 by Luther Wilson Greene, Technical Director of the Chemical and Radiological Laboratories at Edgewood. Greene called for a search for novel psychoactive compounds that would create the same debilitating mental side effects as those produced by nerve gases, but without their lethal effect. In his words,
Throughout recorded history, wars have been characterized by death, human misery, and the destruction of property; each major conflict being more catastrophic than the one preceding it ... I am convinced that it is possible, by means of the techniques of psychochemical warfare, to conquer an enemy without the wholesale killing of his people or the mass destruction of his property.[2]
In the late 1940s and early '50s, the U.S. Army worked with Harvard anesthesiologist Henry K. Beecher at its interrogation center at Camp King in Germany on the use of psychoactive compounds (mescaline, LSD), including human subject experiments and the debriefing of former Nazi physicians and scientists who had worked along similar lines before the end of the war.[3] In the 1950s, some officials in the U.S. Department of Defense publicly asserted that many "forms of chemical and allied warfare as more 'humane' than existing weapons. For example, certain types of 'psychochemicals' would make it possible to paralyze temporarily entire population centers without damage to homes and other structures."[4] Soviet advances in the same field were cited as a special incentive giving impetus to research efforts in this area, according to testimony by Maj. Gen. Marshall Stubbs, the Army's chief chemical officer.
General William M. Creasy, former chief chemical officer, U.S. Army, testified to the U.S. House of Representatives in 1959 that "provided sufficient emphasis is put behind it, I think the future lies in the psychochemicals."[5] This was alarming enough to a Harvard psychiatrist, E. James Lieberman, that he published an article entitled "Psychochemicals as Weapons" in The Bulletin of the Atomic Scientists in 1962. Lieberman, while acknowledging that "most of the military data" on the research ongoing at the Army Chemical Center was "secret and unpublished", asserted that "There are moral imponderables, such as whether insanity, temporary or permanent, is a more 'humane' military threat than the usual afflictions of war."[6]
The experiments
The Edgewood Arsenal human experiments took place from approximately 1948 to 1975 at the Medical Research Laboratories—which is now known as the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD)—at the Edgewood Area, Aberdeen Proving Ground, Maryland. The experiments involved at least 254 chemical substances, but focused mainly on midspectrum incapacitants, such as LSD, THC derivatives, benzodiazepines, and BZ. Around 7,000 US military personnel and 1,000 civilians were test subjects over almost three decades.[7][8][9] A concrete result of these experiments was that BZ was weaponized, although never deployed.[10]
According to a DOD FAQ, the Edgewood Arsenal experiments involved the following "rough breakout of volunteer hours against various experimental categories":[11]
Experimental category | Percentage of volunteer hours |
---|---|
Incapacitating compounds | 29.9% |
Lethal compounds | 14.5% |
Riot control compounds | 14.2% |
Protective equipment and clothing | 13.2% |
Development evaluation and test procedures | 12.5% |
Effects of drugs and environmental stress on human physiological mechanisms | 6.4% |
Human factors tests (ability to follow instructions) | 2.1% |
Other (visual studies, sleep deprivation, etc.) | 7.2% |
An "Independent Study Course" for continuing medical education produced by the US Department of Veterans Affairs, Health Effects from Chemical, Biological, and Radiological Weapons (October 2003),[12] presents the following summary of the Edgewood Arsenal experiments:
The "Independent Study Course" cites mainly a three-volume study by the Institute of Medicine (1982–1985) for its data and conclusions, Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents.[13] Some additional information in the section cited from the Course was based on a 1993 IOM study, Veterans at Risk: Health Effects of Mustard Gas and Lewisite.[14]
A significant omission from the Course summary above is the number of subjects on which BZ and related compounds were tested. According to the memoirs of James Ketchum, who also cites the IOM study for the data, "24 belladonnoid glycolates and related compounds" were "given to 1,800 subjects". The IOM study also concluded that "available data suggest that long-term toxic effects and/or delayed sequellae are unlikely" for this type of compound.[15]
In the mid-1970s, in the wake of many health claims made regarding exposure to the agents, the U.S. Congress began investigations of possible abuse in experiments and of inadequate informed consent given to the soldiers and civilians involved.
Scandal and termination
In September 1975, the Medical Research Volunteer Program was discontinued and all resident volunteers were removed from the Edgewood installation. The founder and director of the program, Van Murray Sim, was called before Congress and chastised by outraged lawmakers, who questioned the absence of follow-up care for the human volunteers. An Army investigation subsequently found no evidence of serious injuries or deaths associated with the MRVP, but deplored both the recruiting process and the informed consent approach, which they characterized as "suggest[ing] possible coercion".
Aftermath
Government reports
1982-85 IOM report
The Institute of Medicine (IOM) published a three-volume report on the Edgewood research in 1982–1985, Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents.[16]
The three volumes were:
- Vol. 1, "Anticholinesterases and Anticholinergics" (1982).
- Vol. 2, "Cholinesterase Reactivators, Psychochemicals and Irritants and Vesicants" (1984)
- Vol. 3, "Final Report: Current Health Status of Test Subjects" (1985)
The National Academy of Sciences, which oversees the IOM, sent a questionnaire to all of the former volunteers that could be located, approximately 60% of the total. The lack of a detailed record hampered the investigation. The study could not rule out long-term health effects related to exposure to the nerve agents. It concluded that "Whether the subjects at Edgewood incurred these changes [depression, cognitive deficits, tendency to suicide] and to what extent they might now show these effects are not known". With regard specifically to BZ and related compounds, the IOM study concluded that "available data suggest that long-term toxic effects and/or delayed sequellae are unlikely".
2004 GAO report
A Government Accounting Office report of May 2004, Chemical and Biological Defense: DOD Needs to Continue to Collect and Provide Information on Tests and Potentially Exposed Personnel (pp. 1, 24), stated:
[In 1993 and 1994] we [...] reported that the Army Chemical Corps conducted a classified medical research program for developing incapacitating agents. This program involved testing nerve agents, nerve agent antidotes, psycho chemicals, and irritants. The chemicals were given to volunteer service members at Edgewood Arsenal, Maryland; Dugway Proving Ground, Utah; and Forts Benning, Bragg, and McClellan. In total, Army documents identified 7,120 Army and Air Force personnel who participated in these tests. Further, GAO concluded that precise information on the scope and the magnitude of tests involving human subjects was not available, and the exact number of human subjects might never be known.[17]
Safety debates
The official position of the Department of Defense, based on the three-volume set of studies by the Institute of Medicine mentioned above, is that they "did not detect any significant long-term health effects on the Edgewood Arsenal volunteers".[9] The safety record of the Edgewood Arsenal experiments was also defended in the memoirs of psychiatrist and retired colonel James Ketchum, a key scientist:[18]
As late as 2014 incomplete information due to the failure to declassify and release relevant classified documents prevented IOM from conducting adequate medical studies related to similar former US biowarfare programs.
Even a book critical of the program, written by Lynn C. Klotz and Edward J. Sylvester, acknowledges that:
Unlike the CIA program, research subjects [at Edgewood] all signed informed consent forms, both a general one and another related to any experiment they were to participate in. Experiments were carried out with safety of subjects a principal focus. [...] At Edgewood, even at the highest doses it often took an hour or more for incapacitating effects to show, and the end-effects usually did not include full incapacitation, let alone unconsciousness. After all, the Edgewood experimenters were focused on disabling soldiers in combat, where there would be tactical value simply in disabling the enemy.[8]
Lawsuits
The U.S. Army believed that legal liability could be avoided by concealing the experiments. However once the experiments were uncovered, the US Senate also concluded questionable legality of the experiments and strongly condemned them.Шаблон:Quote
In the 1990s, the law firm Morrison & Foerster agreed to take on a class-action lawsuit against the government related to the Edgewood volunteers. The plaintiffs collectively referred to themselves as the "Test Vets".
In 2009 a lawsuit was filed by veterans rights organizations Vietnam Veterans of America, and Swords to Plowshares, and eight Edgewood veterans or their families against CIA, the U.S. Army, and other agencies. The complaint asked the court to determine that defendants' actions were illegal and that the defendants have a duty to notify all victims and to provide them with health care. In the suit, Vietnam Veterans of America, et al. v. Central Intelligence Agency, et al. Case No. CV-09-0037-CW, U.S.D.C. (N.D. Cal. 2009), the plaintiffs did not seek monetary damages. Instead, they sought only declaratory and injunctive relief and redress for what they claimed was several decades of neglect and the U.S. government's use of them as human guinea pigs in chemical and biological agent testing experiments.
The plaintiffs cited:
- The use of troops to test nerve gas, psychochemicals, and thousands of other toxic chemical or biological substances.
- A failure to secure informed consent and other widespread failures to follow the precepts of U.S. and international law regarding the use of human subjects, including the 1953 Wilson Directive and the Nuremberg Code.
- A refusal to satisfy their legal and moral obligations to locate the victims of experiments or to provide health care or compensation to them
- A deliberate destruction of evidence and files documenting their illegal actions, actions which were punctuated by fraud, deception, and a callous disregard for the value of human life.
On July 24, 2013, United States District Court Judge Claudia Wilken issued an order granting in part and denying in part plaintiffs' motion for summary judgment and granting in part and denying in part defendants' motion for summary judgment. The court resolved all of the remaining claims in the case and vacated trial. The court granted the plaintiffs partial summary judgment concerning the notice claim: summarily adjudicating in plaintiffs' favor, finding that "the Army has an ongoing duty to warn" and ordering "the Army, through the DVA or otherwise, to provide test subjects with newly acquired information that may affect their well-being that it has learned since its original notification, now and in the future as it becomes available". The court granted the defendants' motion for summary judgment with respect to the other claims.[19]
On appeal in Vietnam Veterans of America v. Central Intelligence Agency, a panel majority held in July 2015 that Army Regulation 70-25 (AR 70-25) created an independent duty to provide ongoing medical care to veterans who participated in U.S. chemical and biological testing programs. The prior finding held that the Army has an ongoing duty to seek out and provide "notice" to former test participants of any new information that could potentially affect their health.[20]
Material Testing Program EA (Edgewood Arsenal) numbers
Шаблон:Expand list Шаблон:Div col
- EA 229 - Levinstein Mustard (H)
- EA 773 - Agent TB
- EA 1019 - Thiodiglycol
- EA 1033 - Distilled Mustard (HD)
- EA 1034 - Lewisite (L)
- EA 1036 - O-mustard
- EA 1152 - Diisopropyl fluorophosphate (DFP)
- EA 1053 - Nitrogen mustard 3
- EA 1205 - Tabun (GA)
- EA 1207 - O-ethylsarin (VX-G)
- EA 1208 - Sarin (GB)
- EA-1209 - Ethylsarin (GE)
- EA 1210 - Soman (GD)
- EA-1211 - GH
- EA 1212 - Cyclosarin (GF)
- EA 1213 - 2,2-Dimethylpropyl methylphosphonofluoridate (dimebu, neopentyl sarin)
- EA 1214 - 2-Ethylhexyl methylphosphonofluoridate
- EA 1221 - O-isopentyl sarin
- EA 1224 - DMMP
- EA 1230 - 2-Phenoxyethyl methylphosphonofluoridate
- EA 1232 - Methylsarin
- EA 1244 - O-Tabun-ethylenechlorohydrin
- EA-1245 - O-methyl diethyltabun
- EA 1246 - G-agent S
- EA 1249 - 2-Methylpropyl methylphosphonofluoridate
- EA 1250 - Diisopropyl methylphosphonate (DIMP)
- EA 1251 - Difluoro, Difluor, DF or DIF
- EA 1253 - Dichloro, Dichlor, DC, DCl or DICl.
- EA 1255 - sec-butyl sarin
- EA 1256 - A organophosphonate
- EA 1258 - O-butylsarin
- EA 1259 - A organophosphonate
- EA 1261 - O-propylsarin
- EA 1262 - O-hexylsarin
- EA 1263 - O-decylsarin
- EA 1264 - 4-(2,6-Dimethylheptyl) methylphosphonofluoridate
- EA 1274 - 2-Pentyl methylphosphonofluoridate
- EA 1277 - Excelsior
- EA 1285 - Tetraethyl pyrophosphate (TEPP)
- EA 1296 - Tenamfetamine
- EA 1297 - Methylenedioxyphenethylamine
- EA 1298 - Methylenedioxyamphetamine (MDA), an analogue and active metabolite of MDMA
- EA 1299 - EA-1298 (S)-form
- EA 1302 - 3-methoxyphenethylamine
- EA 1304 - 3,4-methylenedioxyphenyl-2-butanamine
- EA 1306 - Mescaline
- EA 1316 - 3,4-Dimethoxyamphetamine
- EA 1319 - alpha-Methylmescaline
- EA 1322 - 3,4-dimethoxypropylamine
- EA 1356 - (Racemic) 2-Methylcyclohexyl methylphosphonofluoridate
- EA 1370 - G-agent
- EA 1407 - Vomiting agent
- EA 1464 - A quaternary ammonium carbamate nerve agent[21]
- EA 1465 - A THC derivative
- EA 1473 - A quaternary ammonium carbamate nerve agent[22]
- EA 1475 - Methylenedioxymethamphetamine
- EA 1476 - Dimethylheptylpyran
- EA 1477 - A THC derivative
- EA 1507 - A carbamate THC derivative
- EA 1508 - VG
- EA 1511 - VP
- EA 1512 - A V-agent
- EA 1517 - VE
- EA 1518 - A V-agent
- EA 1519 - A V-agent
- EA 1520 - A V-agent
- EA 1521 - A V-agent
- EA 1522 - A V-agent
- EA 1523 - A V-agent
- EA 1533 - A V-agent
- EA 1542 - A THC derivative
- EA 1543 - A V-agent derived from THC
- EA 1544 - A THC derivative
- EA 1545 - A THC derivative
- EA 1576 - A V-agent derived from mevinphos
- EA 1599 - V-agent
- EA 1622 - O-Isopropyl S-(diethylaminoethyl) methylphosphonothioate
- EA 1635 - V-agent
- EA 1636 - V-agent
- EA 1653 - LSD in tartrate form[23]
- EA 1664 - Edemo (VM)
- EA 1671 - A solid V-agent
- EA 1675 - A solid V-agent
- EA 1676 - V-agent
- EA 1677 - VS, a "V-series" nerve agent
- EA 1679 - V-agent
- EA 1680 - V-agent
- EA 1694 - EthylVx
- EA 1695 - V-agent
- EA 1697 - V-agent
- EA 1698 - V-agent
- EA 1699 - Vx (V5)
- EA 1700 - V-agent
- EA 1701 - VX
- EA 1703 - V-agent
- EA 1724 - QL
- EA 1728 - V2
- EA 1729 - LSD in free base form
- EA 1763 - V1
- EA 1778 - Nonanoyl morpholide
- EA 1788 - Organophosphonate
- EA 1779 - CS gas
- EA 1811 - Quaternary oxime
- EA 1813 - Quaternary oxime
- EA 1814 - TMB4
- EA 1821 - Pralidoxime iodide
- EA 1941 - Quaternary oxime
- EA 1972 - Dimethyl diglycolate (DG) [24]
- EA 2012 - bis-Quaternary ammonium phosphonate
- EA 2054 - bis-Quaternary ammonium phosphonate
- EA 2071 - Pralidoxime lactate
- EA 2092 - Benactyzine
- EA 2097 - Benzylidene malonitrile (CS14632)
- EA 2098 -bis-Quaternary ammonium phosphonate
- EA 2129 - Respiratory irritant
- EA 2148 - Phencyclidine (PCP)[25]
- EA 2170 - Pralidoxime Chloride
- EA 2172 - A incapacitating agent
- EA 2192 - VX O-hydrolysis product
- EA 2214 - Respiratory irritant
- EA 2216 - A incapacitating agent
- EA 2217 - A incapacitating agent
- EA 2218 - A incapacitating agent
- EA 2219 - A incapacitating agent (analgesic potency = 63.3)
- EA 2221 - A incapacitating agent (analgesic potency = 158)
- EA 2222 - Methylthiosarin
- EA 2223 - Thiocyclosarin
- EA 2227 - A incapacitating agent
- EA 2228 - A incapacitating agent (analgesic potency = 200)
- EA 2230 - A incapacitating agent (analgesic potency = 3125)
- EA 2233 - Acetyl dimethylheptylpyran
- Eight individual isomers numbered EA-2233-1 through EA-2233-8
- EA 2235 - A incapacitating agent
- EA 2236 - Incapacitating agent
- EA 2237 - A incapacitating agent
- EA 2238 - A incapacitating agent
- EA 2240 - A incapacitating agent
- EA 2261 - Thio-EA-1356
- EA 2264 - Incapacitating agent
- EA 2265 - Incapacitating agent
- EA 2276 - V-agent
- EA 2277 - BZ ("Substance 78" to Soviets)
- EA 2284 - Lacrimatory agent
- EA 2302 - Lacrimatory agent
- EA 2305 - Lacrimatory agent
- EA 2306 - (-)-BZ
- EA 2329 - Lacrimatory agent
- EA 2333 - (+)-BZ
- EA 2337 - Thiosoman (GDS or TGD)
- EA 2361 - TGS or GSS
- EA 2362 - Incapacitating agent
- EA 2363 - Incapacitating agent
- EA 2364 - Incapacitating agent
- EA 2366 - Lacrimatory agent
- EA 2389 - Incapacitating agent
- EA 2391 - Incapacitating agent
- EA 2392 - Incapacitating agent
- EA 2393 - Incapacitating agent
- EA 2405 - Incapacitating agent
- EA 2407 - Incapacitating agent
- EA 2413 - Lacrimatory agent
- EA 2419 - Lacrimatory agent
- EA 2422 - Incapacitating agent
- EA 2433 - Lacrimatory agent
- EA 2442 - Incapacitating agent
- EA 2464 - Incapacitating agent
- EA 2475 - Incapacitating agent (analgesic potency = 17860)
- EA 2535 - Incapacitating agent
- EA 2542 - 2-Bromoethyl bromoacetamide
- EA 2545 - Incapacitating agent
- EA 2580 - A incapacitating agent
- EA 2613 - bis-Quaternary ammonium phosphonate
- EA 2615 - Incapacitating agent
- EA 2664 - Alkoxyarylamino analog of the Etonitazene (Analgesic potency = 312.5)
- EA 3000 - Botulinum toxin
- EA 3148 - A "V-series" nerve agent, Cyclopentyl S-2-diethylaminoethyl methylphosphonothiolate ("Substance 100A" to Soviets)
- EA 3164 - Incapacitating agent
- EA 3167 - A BZ variant
- EA 3171 - Incapacitating agent
- EA 3176 - Lacrimatory agent
- EA 3186 - Incapacitating agent
- EA 3209 - A bis-quaternary ammonium phosphonate nerve agent
- EA 3287 - Incapacitating agent
- EA 3305 - 2,5-Dimethylcyclohexyl methylphosphonofluoridate
- EA 3306 - Incapacitating agent
- EA 3307 - A irritant agent
- EA 3309 - Incapacitating agent
- EA 3317 - V-agent
- EA 3364 - Incapacitating agent
- EA 3365 - Lacrimatory agent
- EA 3367 - Incapacitating agent
- EA 3382 - Incapacitating agent
- EA 3387 - Incapacitating agent
- EA 3407 - Incapacitating agent
- EA 3430 - 2-Methylcyclopentyl methylphosphonofluoridate
- EA 3437 - Respiratory irritant
- EA 3439 - Incapacitating agent
- EA 3441 - Incapacitating agent
- EA 3443 - A BZ variant
- EA 3473 - Quaternary ammonium analog of the Etonitazene
- EA 3475 - Toxogonin
- EA 3480 - Incapacitating agent
- EA 3528 - LSD in maleate form
- EA 3525 - Incapacitating agent
- EA 3534 - G-agent
- EA 3536 - Quaternary ammonium analog of the Etonitazene
- EA 3547 - CR gas
- EA 3561 - A blood agent
- EA 3562 - A blood agent
- EA 3563 - A blood agent
- EA 3564 - A blood agent
- EA 3565 - A blood agent
- EA 3566 - A blood agent
- EA 3567 - A blood agent
- EA 3568 - A blood agent
- EA 3569 - A blood agent
- EA 3570 - A blood agent
- EA 3571 - A blood agent
- EA 3572 - A blood agent
- EA 3580 - A BZ variant
- EA 3625 - A irritant agent
- EA 3631 - A incapacitating agent
- EA 3632 - A blood agent
- EA 3633 - A blood agent
- EA 3634 - A blood agent
- EA 3635 - A blood agent
- EA 3636 - A blood agent
- EA 3637 - A blood agent
- EA 3638 - A blood agent
- EA 3639 - A blood agent
- EA 3640 - A blood agent
- EA 3641 - A blood agent
- EA 3669 - EA-1464 oxalate salt[21]
- EA 3695 - BZ analogue
- EA 3729 - A blood agent
- EA 3730 - A blood agent
- EA 3731 - A blood agent
- EA 3732 - A blood agent
- EA 3733 - A blood agent
- EA 3734 - A blood agent
- EA 3735 - A blood agent
- EA 3736 - A blood agent
- EA 3737 - A blood agent
- EA 3738 - A blood agent
- EA 3739 - A blood agent
- EA 3740 - A blood agent
- EA 3741 - A blood agent
- EA 3742 - A blood agent
- EA 3743 - A blood agent
- EA 3744 - A blood agent
- EA 3745 - A blood agent
- EA 3746 - A blood agent
- EA 3747 - A blood agent
- EA 3748 - A blood agent
- EA 3749 - A blood agent
- EA 3750 - A blood agent
- EA 3751 - A blood agent
- EA 3752 - A blood agent
- EA 3753 - A blood agent
- EA 3754 - A blood agent
- EA 3755 - A blood agent
- EA 3827 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 3828 - A bis-Quaternary ammonium carbamate nerve agent
- EA 3831 - Polymethylene bis-Quaternary Ammonium Compound
- EA 3834 - A BZ variant
- EA 3859 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 3861 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 3887 - A bis-Quaternary ammonium carbamate nerve agent
- EA 3887-A - A bis-Quaternary ammonium carbamate nerve agent
- EA 3940 - Palytoxin
- EA 3947 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 3948 - A bis-Quaternary ammonium carbamate nerve agent
- EA 3958 - Polymethylene bis-Quaternary Ammonium Compound
- EA 3966 - A bis-Quaternary ammonium carbamate nerve agent
- EA 3990 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4026 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4038 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4046 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4048 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4050 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4056 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4057 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4059 - alpha-methylene analog of the Etonitazene
- EA 4067 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4075 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4076 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4079 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4080 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4081 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4082 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4113 - A analog of the Etonitazene
- EA 4129 - Dialkylamino analog of the Etonitazene
- EA 4165 - alpha-Hydroxy analog of the Etonitazene
- EA 4177 - A analog of the Etonitazene
- EA 4181 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4196 - bis(diisopropylaminoethyl) disulfide
- EA 4232 - Etonitazene precursor
- EA 4243 - V-agent
- EA 4245 - A analog of the Etonitazene
- EA 4349 - Cyclooctyl methylphosphonofluoridate (Candidate G-agent S No.1)
- EA 4352 - G-agent
- EA 4557 - A analog of the Etonitazene
- EA 4684 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4691 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4718 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4719 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4720 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4789 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4831 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4832 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4833 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4858 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4859 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4870 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4873 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4874 - A bis-Quaternary ammonium carbamate nerve agent
- EA 4879 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4881 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4882 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4883 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4885 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4910 - Metonitazene precursor
- EA 4913 - Decamethylene-2,9-Dione bis-Quaternary Ammonium Compound
- EA 4916 - Alkoxyarylamino analog of the Etonitazene
- EA 4919 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4920 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 4921 - CHT inert isomer
- EA 4922 - CHT inert isomer
- EA 4923 - CHT gas
- EA 4929 - Benzetimide
- EA 4937 - Alkoxyarylamino analog of the Etonitazene (Analgesic potency = 55)
- EA 4941 - Etonitazene (free base)
- EA 4977 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4978 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4979 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4980 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4981 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4984 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4985 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4986 - Alkoxyarylamino analog of the Etonitazene
- EA 4987 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4988 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4989 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4992 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4993 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4994 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 4995 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4996 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 4997 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 5006 - alpha-Hydroxy analog of the Etonitazene (Analgesic potency = 17)
- EA 5011 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 5014 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 5015 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 5016 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 5019 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 5020 - Phenacyl Mono-Quaternary Ammonium Compound
- EA 5033 - alpha-Hydroxy analog of the Etonitazene
- EA 5049 - Biphenacyl bis-Quaternary Ammonium Compound
- EA 5094 - Phenyl-Phenacyl Mono-Quaternary Ammonium Compound
- EA 5147 - Polymethylene bis-Quaternary Ammonium Compound
- EA 5155 - alpha-Hydroxy analog of the Etonitazene
- EA 5167 - Neuroleptic agent
- EA 5194 - Neuroleptic agent
- EA 5195 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5199 - Polymethylene bis-Quaternary Ammonium Compound
- EA 5202 - Neuroleptic agent
- EA 5211 - Neuroleptic agent
- EA 5225 - Neuroleptic agent
- EA 5236 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5243 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5244 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5245 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5265 - 2,4-Dimethylcyclohexyl methylphosphonofluoridate
- EA 5270 - alpha-Hydroxy analog of the Etonitazene (Analgesic Potency = 1000)
- EA 5298 - Phenacyl Butanone bis-Quaternary Ammonium Compound
- EA 5299 - Phenylenediacetyl bis-Quaternary Ammonium Compound
- EA 5302 - 33% EA-3834B and 67% EA-4923
- EA 5309 - Neuroleptic agent
- EA 5310 - Neuroleptic agent
- EA 5320 - Neuroleptic agent
- EA 5340 - Neuroleptic agent
- EA 5345 - Unsymmetrical bis-Quaternary Ammonium Compound
- EA 5352 - Unsymmetrical bis-Quaternary Ammonium Compound
- EA 5355 - Neuroleptic agent
- EA 5360 - Neuroleptic agent
- EA 5365 - G-agent V
- EA 5366 - GV methylated to iodide salt
- EA 5371 - Phenylenediacetyl bis-Quaternary Ammonium Compound
- EA 5382 - Phenylenediacetyl bis-Quaternary Ammonium Compound
- EA 5389 - Thio-EA 5265
- EA 5398 - Unsymmetrical bis-Quaternary Ammonium Compound
- EA 5400 - G-agent X
- EA 5403 - 1,1-Dimethylamino-2-propyl N,N-dimethylphosphoramidofluoridate
- EA 5410 - GV-agent
- EA 5414 - GV4
- EA 5432 - Neuroleptic agent
- EA 5443 - A bis-unsymmetrical isoquinoline carbamate
- EA 5444 - Neuroleptic agent
- EA 5448 - Unsymmetrical bis-Quaternary Ammonium Compound
- EA 5458 - GVX
- EA 5471 - A bis-unsymmetrical isoquinoline carbamate
- EA 5474 - A bis-symmetrical isoquinoline carbamate
- EA 5475 - A bis-symmetrical isoquinoline carbamate
- EA 5476 - A bis-symmetrical isoquinoline carbamate
- EA 5478 - V-sub agent T
- EA 5479 - A bis-symmetrical isoquinoline carbamate
- EA 5480 - A bis-symmetrical isoquinoline carbamate
- EA 5481 - A bis-symmetrical isoquinoline carbamate
- EA 5482 - A bis-symmetrical isoquinoline carbamate
- EA 5483 - A bis-symmetrical isoquinoline carbamate
- EA 5484 - A bis-symmetrical isoquinoline carbamate
- EA 5485 - A bis-symmetrical isoquinoline carbamate
- EA 5488 - GV-O-Quinuclidinyl
- EA 5490 - Unsymmetrical bis-Quaternary Ammonium Compound
- EA 5492 - A bis-unsymmetrical isoquinoline carbamate
- EA 5493 - A bis-unsymmetrical isoquinoline carbamate
- EA 5494 - A bis-unsymmetrical isoquinoline carbamate
- EA 5502 - A GV agent derivative
- EA 5506 - A bis-unsymmetrical isoquinoline carbamate
- EA 5511 - GV-agent
- EA 5533 - V-agent
- EA 5540 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5579 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5581 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5582 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5583 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5584 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5585 - Tetra-quaternary ammonium isoquinoline carbamate
- EA 5586 - Octa-quaternary ammonium isoquinoline carbamate
- EA 5615 - EA-5365 precursor candidate
- EA 5636 - EA-5365 precursor candidate
- EA 5696 - Morphine related compound
- EA 5752 - IR metallic smoke
- EA 5753 - IR metallic smoke
- EA 5753D - Dedusted IR metallic smoke
- EA 5755 - IR metallic smoke
- EA 5761 - Organophosphonate binary
- EA 5763 - IR metallic smoke
- EA 5763D - Dedusted IR metallic smoke
- EA 5768 - IR graphite smoke
- EA 5769 - IR metallic smoke
- EA 5774 - Soman binary
- EA 5774-T - Thickened soman binary
- EA 5823 - Sarin (GB) as a binary agent from mixing OPA (isopropyl alcohol+isopropyl amine) + DF
- EA 5824 - EA-1356 binary
- EA 5824-T - EA-1356 binary PMMA thickened
- EA 5825 - Organophosphonate binary.
- EA 5826 - Organophosphonate binary.
- EA 5830 - EA 1699 binary.
- EA 5852 - EA 1210 + EA 1356 binary
- EA 5864 - Irritant agent
- EA 5874 - Carbamate nerve agent
- EA 5928 - Isopropyl tert-butylphosphonofluoridate
- EA 5944 - G-agent simulant
- EA 5945 - G-agent simulant
- EA 5957 - A mustard agent
- EA 5968 - A IR graphite smoke
- EA 5978 - Incapacitating agent
- EA 5983 - A mustard agent
- EA 5992 - A mustard agent
- EA 5995 - Incapacitating agent
- EA 5999 - Titanium dioxide smoke
- EA 6030 - G-agent
- EA 6043 - V-agent
- EA 6095 - A mercaptan related compound
See also
- THC-O-acetate
- CB military symbol
- United States chemical weapons program
- Edgewood Chemical Biological Center
- Human experimentation in the United States
- Swords to Plowshares
- United States v. Stanley
References
General sources
- Two autobiographical books from psychiatrists conducting human experiments at Edgewood have been self-published:
- Men and Poisons: The Edgewood Volunteers and the Army Chemical Warfare Research Program (2005), Xlibris Corporation, 140pp, was written by Malcolm Baker Bowers Jr, who went on to become a prof of psychiatry at Yale.[26] Bowers' book is a "fictionalized" account with names changed.Шаблон:Citation needed
- Chemical Warfare Secrets Almost Forgotten, A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War (1955–1975) (2006, 2nd edition 2007), foreword by Alexander Shulgin, ChemBook, Inc., 360 pp, was written by Ketchum who was a key player after 1960 and went on to become a professor at the University of California, Los Angeles.
- The Vanderbilt University Television News Archive has two videos about the experiments, both from a July 1975 NBC Evening News segment.[27]
- NBC newsman John Chancellor reported on how Norman Augustine, then-acting Secretary of Army, ordered a probe of Army use of LSD in soldier and civilian experiments.
- Correspondent Tom Pettit reported on Major General Lloyd Fellenz, from Edgewood Arsenal, who explained how the experiments there were about searching for humane weapons, adding that the use of LSD was unacceptable.
- Journalist Linda Hunt, citing records from the U.S. National Archives, revealed that eight German scientists worked at Edgewood, under Project Paperclip.[28] Hunt used this finding to assert that in this collaboration, US and former Nazi scientists "used Nazi science as a basis for Dachau-like experiments on over 7,000 U.S. soldiers".[29]
- A The Washington Post article, dated July 23, 1975, by Bill Richards ("6,940 Took Drugs") reported that a top civilian drug researcher for the Army said a total of 6,940 servicemen had been involved in Army chemical and drug experiments, and that, furthermore, the tests were proceeding at Edgewood Arsenal as of the date of the article.
- Two TV documentaries, with different content but confusingly similar titles were broadcast:
- In 2012, the Edgewood/Aberdeen experiments were featured on CNN and in The New Yorker magazine.[19][34][35][36][37][38][39][40]
Citations
External links
- Edgewood Test Vets: Vietnam Veterans of America, et al. v. Central Intelligence Agency, et al. Case No. CV-09-0037-CW, U.S.D.C. (N.D. Cal. 2009), Morrison & Foerster LLP, August 7, 2013
- Hunt, Secret Agenda: The U.S. Government, Nazi Scientists and Project Paperclip 1945-1991.Шаблон:Dead link
- Secrets of Edgewood, The New Yorker, December 26, 2012
- Edgewood/Aberdeen Experiments, U.S. Department of Veterans Affairs
- David S. Martin, Vets feel abandoned after secret drug experiments, CNN, March 1, 2012
- Tom Bowman, Former sergeant seeks compensation for LSD testing at Edgewood Arsenal Шаблон:Webarchive, July 11, 1991, The Baltimore Sun
Шаблон:U.S. chemical weapons Шаблон:Cannabis and the military
- ↑ 1,0 1,1 Шаблон:Cite web
- ↑ Greene, L. Wilson, "Psychochemical Warfare: A New Concept of War", U. S. Army Chemical Center, Edgewood Arsenal, Maryland; August 1949.
- ↑ George A. Mashour (2009), "Altered States: LSD and the Anesthesia Laboratory of Henry Knowles Beecher" Шаблон:Webarchive, CSA Bulletin, Winter issue, pp 68-74.
- ↑ "US Plans Study of Gas Warfare" Шаблон:Webarchive [New York Times News Service], Sunday, 9 August 1959, The Milwaukee Journal, Part I, pg 2.
- ↑ "Chemical, Biological, and Radiological Warfare Agents", Hearings before the Committee on Science and Astronautics, U.S. House of Representatives, June 1959 (No. 22).
- ↑ Lieberman, E. James (1962), "Psychochemicals as Weapons"; Bulletin of the Atomic Scientists (January issue).
- ↑ Шаблон:Cite book
- ↑ 8,0 8,1 Шаблон:Cite book
- ↑ 9,0 9,1 Шаблон:Cite web
- ↑ Researchers tested pot, LSD on Army volunteers Richard Willing, USA Today, 4/6/2007
- ↑ Edgewood Arsenal Chemical Agent Exposure Studies FAQs. What types of tests were conducted at Edgewood? Шаблон:Webarchive September 08, 2008
- ↑ "Health Effects from Chemical, Biological, and Radiological Weapons", U.S. Department of Veterans Affairs (October 2003), page 6.
- ↑ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Commission on Life Sciences. The National Academies Press. In three volumes:
- ↑ Veterans at Risk: Health Effects of Mustard Gas and Lewisite, National Academy of Sciences, Institute of Medicine, National Academy Press, Washington, D.C., 1993, 427 pp.
- ↑ Шаблон:Cite book
- ↑ Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents, Commission on Life Sciences. The National Academies Press. In three volumes:
- ↑ Chemical and Biological Defense, Government Accounting Office, May 2004, p. 24.
- ↑ Шаблон:Cite book citing Шаблон:Cite book
- ↑ 19,0 19,1 Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ 21,0 21,1 Sommer, Harold Z. Krenzer, John Miller, Jacob I. EA 1464 and Related Compounds. II. Improved Synthesis of EA 1464 and Preparation of its Corresponding Di-(Hydrogen Oxalate) Salt, EA 3669
- ↑ Krenzer, John Miller, Jacobi Natarelli, G. E. EA 1464 and Related Compounds, I. Synthesis of EA 1464, EA 1473, and Their Homologs.
- ↑ Шаблон:Cite journal
- ↑ Expert meeting report. "Incapacitating chemical agents": Law enforcement, human rights law and policy perspectives. pp 89
- ↑ Шаблон:Cite journal
- ↑ Шаблон:Cite magazine
- ↑ "July 17, 1975 NBC Evening News segment", Vanderbilt University, July 17, 1975.
- ↑ Secret Agenda: the United States Government, Nazi Scientists and Project Paperclip St. Martin's Press, 1991; ABC PrimeTime Live, Operation Paperclip, 1991, and hearings before the House Judiciary Committee, 1991.
- ↑ Шаблон:Cite book
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ "Secret Army volunteer's widow blames VA for spouse's death" (CNN; 3/3/12)
- ↑ "Vets feel abandoned after secret drug experiments" (CNN; 3/1/12)
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