Английская Википедия:Elfazepam

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Шаблон:Short description Шаблон:Drugbox

Elfazepam[1] is a drug which is a benzodiazepine derivative.[2] Presumably it has sedative and anxiolytic actions like those of other benzodiazepines.

Orexigenic properties in animals.[3][4] The mechanism for increasing feed intake is not clear and has been subject of investigation.[5] It has been found that elfazepam suppresses gastric acid secretion.[6]

Synthesis

Файл:Elfazepam synthesis.svg
Elfazepam synthesis: U.S. Patent 4,010,154

Benzophenone derivative 1 is reacted with a glycine equivalent masked as an oxazolidine-2,5-dione 2 to give the final product 3 Elfazepam.

References

Шаблон:Reflist

Шаблон:Benzodiazepines Шаблон:GABAAR PAMs

Шаблон:Sedative-stub