Английская Википедия:Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)

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Шаблон:Short description Шаблон:Infobox enzyme In enzymology, an enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

acyl-[acyl-carrier-protein] + NADP+ <math>\rightleftharpoons</math> trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADPH + H+

Thus, the two substrates of this enzyme are [[acyl-[acyl-carrier-protein]]] and NADP+, whereas its 3 products are [[trans-2,3-dehydroacyl-[acyl-carrier-protein]]], NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (B-specific). Other names in common use include acyl-ACP dehydrogenase, reductase, enoyl-[acyl carrier protein] (reduced nicotinamide, adenine dinucleotide phosphate), NADPH 2-enoyl Co A reductase, enoyl acyl-carrier-protein reductase, enoyl-ACP reductase, and enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific). This enzyme participates in fatty acid biosynthesis.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:CH-CH oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.3-enzyme-stub