Английская Википедия:Estradiol benzoate/hydroxyprogesterone caproate

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Estradiol benzoate/hydroxyprogesterone caproate (EB/OHPC), sold under the brand name Primosiston among others, is a combined estrogen and progestogen medication which is used to treat gynecological disorders and habitual abortion.[1][2][3][4][5] It contains estradiol benzoate (EB), an estrogen, and hydroxyprogesterone caproate (OHPC), a progestin.[1][2][3][4][5] The medication is given by injection into muscle.[1][2][3][4][5]

Medical uses

EB/OHPC is used in the treatment of gynecological disorders such as menstrual disorders (e.g., amenorrhea, dysfunctional uterine bleeding) and premenstrual syndrome, habitual abortion (threatened miscarriage), and for other indications.[1][2][3][4]

Available forms

EB/OHPC is available in the form of ampoules of oil solutions containing 10 mg estradiol benzoate (EB) and 125 to 250 mg hydroxyprogesterone caproate (OHPC).[1][2][3][4][5]

History

EB/OHPC was first introduced for medical use in 1955.[6]

Society and culture

Brand names

EB/OHPC has been marketed under brand names including Dos Dias N, Lutes, Ostrolut, Primosiston (or Primosiston Inj. / Injection), Primosiston Fuerte, and Syngynon.[7][8][9]

Availability

EB/OHPC has been mostly discontinued and hence is mostly no longer available.[7][8][9] It remains marketed under the brand names Primosiston in Ecuador and Peru, Dos Dias N in Argentina, and Lutes in Japan.[7][8][9] It was previously marketed under the brand names Ostrolut in Austria; Primosiston (or Primosiston Inj. / Injection) (Schering)[1][2][4] in Argentina, Germany, Mexico, Switzerland, and Venezuela; Primosiston Fuerte in Spain; and Syngynon in Germany, but these formulations have all been discontinued and hence are no longer available in these countries.[7][8][9]

See also

References

Шаблон:Reflist

Шаблон:Estrogens and antiestrogens Шаблон:Progestogens and antiprogestogens Шаблон:Estrogen receptor modulators Шаблон:Progesterone receptor modulators

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Партнерские ресурсы
Криптовалюты
Магазины
Хостинг
Разное

  1. ↑ 1,0 1,1 1,2 1,3 1,4 1,5 Шаблон:Cite book
  2. ↑ 2,0 2,1 2,2 2,3 2,4 2,5 Шаблон:Cite book
  3. ↑ 3,0 3,1 3,2 3,3 3,4 Шаблон:Cite book
  4. ↑ 4,0 4,1 4,2 4,3 4,4 4,5 Шаблон:Cite book
  5. ↑ 5,0 5,1 5,2 5,3 Шаблон:Cite book
  6. ↑ Шаблон:Cite journal
  7. ↑ 7,0 7,1 7,2 7,3 Шаблон:Cite web
  8. ↑ 8,0 8,1 8,2 8,3 Шаблон:Cite book
  9. ↑ 9,0 9,1 9,2 9,3 Шаблон:Cite web
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