Английская Википедия:Estradiol phosphate

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Estradiol phosphate, or estradiol 17β-phosphate, also known as estra-1,3,5(10)-triene-3,17β-diol 17β-(dihydrogen phosphate), is an estrogen which was never marketed. It is an estrogen ester, specifically an ester of estradiol with phosphoric acid, and acts as a prodrug of estradiol in the body.[1][2] It is rapidly cleaved by phosphatase enzymes into estradiol upon administration.[1][2] Estradiol phosphate is contained within the chemical structures of two other estradiol esters, polyestradiol phosphate (a polymer of estradiol phosphate) and estramustine phosphate (estradiol 3-normustine 17β-phosphate), both of which have been marketed for the treatment of prostate cancer.[2][3][1]

Шаблон:Structural properties of selected estradiol esters

See also

References

Шаблон:Reflist

Шаблон:Estradiol Шаблон:Estrogen receptor modulators

Шаблон:Genito-urinary-drug-stub Шаблон:Steroid-stub