Английская Википедия:Estrone/progesterone

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Estrone/progesterone (E1/P4), sold under the brand name Synergon, is a combination medication formulation of estrone, an estrogen, and progesterone, a progestogen. E1/P4 is used as an injectable preparation to induce withdrawal bleeding in women with non-pregnancy-related amenorrhea (absence of menstruation).[1][2][3][4] [5][6][7] It has also sometimes been used off-label as an abortifacient.[5][6][8] The medication comes in a three-ampoule pack, contains 1 mg estrone and 10 mg progesterone per ampoule, and is administered by intramuscular injection.[1][5][6][9] The usual dose of the medication is three injections, each two days apart, with the treatment duration not exceeding one week.[1] E1/P4 is or has been available in France, Monaco, and Turkey, as well as in some French-speaking African countries such as Benin and Cameroon.[2][3][4][10][6][8] The medication has been marketed since at least 1952.[11]

See also

References

Шаблон:Reflist

Шаблон:Estrogens and antiestrogens Шаблон:Progestogens and antiprogestogens Шаблон:Estrogen receptor modulators Шаблон:Progesterone receptor modulators

Шаблон:Genito-urinary-drug-stub