Английская Википедия:Faldaprevir

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Шаблон:Short description Шаблон:Drugbox

Faldaprevir was an experimental drug for the treatment of hepatitis C (HCV). It was being developed by Boehringer-Ingelheim and reached Phase III clinical trials in 2011.[1] Boehringer announced in 2014 that it would not pursue approval of the drug any more because of better HCV treatments having become available.[2]

Mechanism of action

Faldaprevir is a hepatitis C virus protease inhibitor.Шаблон:Cn

Studies

Faldaprevir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including deleobuvir.Шаблон:Cn

Data from the SOUND-C2 study, presented at the 2012 AASLD Liver Meeting, showed that a triple combination of faldaprevir, deleobuvir, and ribavirin performed well in HCV genotype 1b patients.[3]

References

Шаблон:Reflist

Шаблон:RNA antivirals