Английская Википедия:Foundation Medicine

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Foundation Medicine, Inc. is an American company based in Cambridge, Massachusetts, which develops, manufactures, and sells genomic profiling assays based on next-generation sequencing technology for solid tumors, hematologic malignancies, and sarcomas.

History

Foundation Medicine was founded in Cambridge, Massachusetts. The company was conceived after Broad Institute researchers Levi Garraway and Matthew Meyerson published a 2007 paper detailing a method for large-panel testing of 238 DNA mutations.

Foundation Medicine launched in 2010 with a $25 million Series A financing led by Third Rock Ventures. The company released its first commercial assay, or test, called FoundationOne in 2012. The company also began partnering with pharmaceutical companies to analyze patient samples. The first such program was piloted with Novartis in 2011, and by 2018, the company had more than 30 partnerships.

Foundation Medicine launched its second test, a hematological biomarker assay called FoundationOneHeme, in 2013. The company held its initial public offering in August 2013. The following year, Priority Health in Michigan became the first healthcare plan in the United States to cover the company's tests.

In 2016, using FoundationCore data, Foundation Medicine released anonymized records detailing genomic data on cancers from 18,000 adult patients to the National Cancer Institute's (NCI) Genomic Data Commons (GDC) portal.

In June 2018, Roche announced it would acquire Foundation Medicine.

Guardant Health sued Foundation Medicine over patents in 2019–2020. In 2021, Guardant Health licensed intellectual property to Foundation Medicine for $25 million in a settlement.

Foundation Medicine is now a subsidiary of Roche and It operates independently.

Products

Foundation Medicine's products include genomic tests used to test solid tumors and blood-based cancers and sarcomas, as well as data services.

• FoundationOne CDx is a CGP test providing information for five tumor types: ovarian, lung, breast, colorectal, and melanoma.
• FoundationOne Liquid
• FoundationOne Heme
• The company's FoundationCore database contains more than 300,000 genomic profiles sourced from the results of the company's assays as well as information on over 150 subtypes of cancer.

External links

• Шаблон:Official website