Английская Википедия:Glibornuride

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Шаблон:Chembox

Glibornuride (INN) is an anti-diabetic drug from the group of sulfonylureas.[1] It is manufactured by MEDA Pharma and sold in Switzerland under the brand name Glutril.[2]

Synthesis

Файл:Glibornuride synthesis.svg
Glibornuride synthesis:[3] See also: Шаблон:US patent; eidem, Шаблон:US patent (to Hoffmann-La Roche).

Gliburnide is an endo-endo derivative made from camphor-3-carboxamide by borohydride reduction (exo approach), followed by Hofmann rearrangement to carbamate, followed by displacement with sodium tosylamide.

References

Шаблон:Reflist

Шаблон:Oral hypoglycemics and insulin analogs Шаблон:Ion channel modulators

Шаблон:Gastrointestinal-drug-stub