Английская Википедия:Global Alliance for Genomics and Health
Шаблон:Short description The Global Alliance for Genomics and Health (GA4GH) is an international consortium that is developing standards for responsibly collecting, storing, analyzing, and sharing genomic data in order to enable an "internet of genomics".[1][2] GA4GH was founded in 2013.[3]
GA4GH is founded on the Framework for the Responsible Sharing of Genomic and Health-related Data,[4] which is based on the human right to benefit from scientific advances.[5]
Organization
GA4GH maintained by four Host Institutions (Wellcome Sanger Institute, Broad Institute, Ontario Institute for Cancer Research and the European Bioinformatics Institute).[6] Heidi Rehm is the current GA4GH chair[7] and Peter Goodhand is the Chief Executive Officer.[8] Kathryn North is the current Vice Chair and Ewan Birney is the past chair.[9]
Organizational members of the alliance include:[6]
Funding
GA4GH is supported by a "Funder's Forum" composed of organizations whose funding commitments exceed USD $200,000 annually, for at least three years. Forum members include:[6]
- Canadian Institutes of Health Research
- Genome Canada
- National Institute for Health Research
- National Institutes of Health
- National Cancer Institute
- National Heart, Lung and Blood Institute
- National Human Genome Research Institute
- Office of Data Science Strategy
- Office of the Director of the National Institutes of Health / All of Us research project
- UK Research and Innovation
- Wellcome Trust
Activities
All GA4GH standards are developed by six technical and two foundational "Work Streams" in collaboration with real-world genomic data initiatives called "Driver Projects."[8]
GA4GH Work Streams
- Regulatory and Ethics (foundational)[7]
- Data Security (foundational)[7]
- Cloud[7]
- Clinical & Phenotypic Data Capture [7]
- Data Use and Researcher Identities[7]
- Discovery[7]
- Genomic Knowledge Standards[7]
- Large Scale Genomics[7]
GA4GH Driver Projects
- All of US Research Program[3]
- Australian Genomics[3]
- BRCA Challenge[3]
- Canadian Distributed Infrastructure for Genomics (CanDig)[3]
- Clinical Genome Resource (ClinGen)[3]
- ELIXIR Beacon[3]
- The European Nucleotide Archive, European Variation Archive, and European Genome-phenome Archive at EMBL-EBI[3]
- EUCANCan [10]
- European Joint Programme on Rare Diseases [11]
- Genomics England[12]
- Human Cell Atlas[12]
- Human Heredity and Health in Africa (H3Africa) [13]
- International Cancer Genome Consortium - ARGO[12]
- Matchmaker Exchange[12]
- The Monarch Initiative[12]
- National Cancer Institute Data Commons Framework (NCI DCF) and Genomic Data Commons (NCI GDC)[12]
- Trans-Omics for Precision Medicine (TOPMed)[12]
- Variant Interpretation for Cancer Consortium (VICC)[12]
References
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ 3,0 3,1 3,2 3,3 3,4 3,5 3,6 3,7 Шаблон:Cite news
- ↑ Шаблон:Cite news
- ↑ Шаблон:Cite web
- ↑ 6,0 6,1 6,2 Шаблон:Cite web
- ↑ 7,0 7,1 7,2 7,3 7,4 7,5 7,6 7,7 7,8 Шаблон:Cite web
- ↑ 8,0 8,1 Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ Шаблон:Cite web
- ↑ 12,0 12,1 12,2 12,3 12,4 12,5 12,6 12,7 Шаблон:Cite web
- ↑ Шаблон:Cite web
