Английская Википедия:Glutamine—pyruvate transaminase

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Шаблон:Infobox enzyme In enzymology, a glutamine-pyruvate transaminase (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

L-glutamine + pyruvate <math>\rightleftharpoons</math> 2-oxoglutaramate + L-alanine

Thus, the two substrates of this enzyme are L-glutamine and pyruvate, whereas its two products are 2-oxoglutaramate and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-glutamine:pyruvate aminotransferase. Other names in common use include glutaminase II, L-glutamine transaminase L, and glutamine-oxo-acid transaminase. This enzyme participates in glutamate metabolism. It employs one cofactor, pyridoxal phosphate.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes Шаблон:PDB link, Шаблон:PDB link, and Шаблон:PDB link.

References

Шаблон:Reflist

Шаблон:Nitrogenous transferases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:2.6-enzyme-stub