Английская Википедия:Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+)

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Шаблон:No footnotes Шаблон:Infobox enzyme In enzymology, a glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (Шаблон:EC number) is an enzyme that catalyzes the chemical reaction

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ <math>\rightleftharpoons</math> 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+

The 4 substrates of this enzyme are D-glyceraldehyde 3-phosphate, phosphate, NAD+, and NADP+, whereas its 4 products are 3-phospho-D-glyceroyl phosphate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating). Other names in common use include (phosphorylating), triosephosphate dehydrogenase (NAD(P)), and glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code Шаблон:PDB link.

References

Шаблон:Reflist

  • P. Mathis (Ed.), Photosynthesis: From Light to Biosphere, vol. 1, Kluwer Academic Publishers, 1995, p. 959-962.
  • Шаблон:Cite journal

Шаблон:Aldehyde/Oxo oxidoreductases Шаблон:Enzymes Шаблон:Portal bar


Шаблон:1.2-enzyme-stub