Английская Википедия:Guanoclor

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Шаблон:Short description Шаблон:Drugbox

Guanoclor (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.[1]

Synthesis

When β-(2,6-dichlorophenoxy)ethyl bromide (1) is reacted with hydrazine to give 2, and this is reacted with S-methylthiourea, guanochlor (3) results.[2][3]

Файл:Guanochlor synthesis.svg
Guanoclor synthesis

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References

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Шаблон:Antihypertensives and diuretics

Шаблон:Antihypertensive-stub

  1. Шаблон:Cite journal
  2. Шаблон:Cite journal
  3. Prepn of free base and sulfate: Шаблон:Cite patent (1963 to Pfizer), C.A. 60, 14437d (1964).