A hybrid mass spectrometer is a device for tandem mass spectrometry that consists of a combination of two or more m/z separation devices of different types.
A sector instrument can be combined with a collision quadrupole and quadrupole mass analyzer to form a hybrid instrument.[1] A BEqQ configuration with a magnetic sector (B), electric sector (E), collision quadrupole (q) and m/z selection quadrupole (Q) have been constructed[2][3] and an instrument with two electric sectors (BEEQ) has been described.[4]
Quadrupole time-of-flight
Файл:Q-TOF.jpgHybrid quadrupole time-of-flight mass spectrometer.
A triple quadrupole mass spectrometer with the final quadrupole replaced by a time-of-flight device is known as a quadrupole time-of-flight instrument.[5][6] Such an instrument can be represented as QqTOF.
Ion trap time-of-flight
In an ion trap instrument, ions are trapped in a quadrupole ion trap and then injected into the TOF. The trap can be 3-D[7] or a linear trap.[8]
Linear ion trap and Fourier transform mass analyzers
Файл:LTQ-FTICR.jpgHybrid linear ion trap Fourier transform ion cyclotron resonance mass spectrometer
