Английская Википедия:Immunomedics
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Immunomedics was a biotechnology company focused on the development of antibody-drug conjugates for the treatment of cancer. In 2020, the company was acquired by Gilead Sciences.[1]
History
Immunomedics was founded in July 1982 by David M. Goldenberg.[2]
Michael Pehl was named CEO in December 2017 but left due to personal reasons in February 2019.[3] At that time, Dr. Behzad Aghazadeh was named Executive Chairman.[4]
In October 2020, Gilead Sciences acquired the company.[1] In March 2022, Gilead announced the closing of the former Immunomedics facility in Morris Plains. [5]
Products
- Epratuzumab is a humanized anti-CD22 monoclonal antibody in phase III trials for pediatric leukemia.Шаблон:Citation needed
- Sacituzumab govitecan (IMMU-132 / Trodelvy) is an anti-Trop-2-SN-38 antibody-drug conjugate for breast cancer and solid tumors. It was approved in April 2020 by the FDA for the treatment of adult patients with metastatic triple-negative breast cancer (mTNBC) who have received at least two prior therapies for patients with relapsed or refractory metastatic disease.[6] In 2017, the company scrapped a licensing deal for the drug with Seagen that led to the resignation of founder David M. Goldenberg.[7]
- Labetuzumab (IMMU-130) is an anti-CEACAM5-SN-38 antibody-drug conjugate in clinical trials for colorectal cancer.Шаблон:Citation needed
- Veltuzumab is an anti-CD20 monoclonal antibody for treatment of cancer.Шаблон:Citation needed
- Milatuzumab (IMMU-110) is an anti-CD74 monoclonal antibody for autoimmune diseases.Шаблон:Citation needed
- IMMU-114 is an anti-HLA-DR for hematological cancers.[8]
References
Категории:
- Английская Википедия
- 1982 establishments in New Jersey
- 2020 mergers and acquisitions
- American companies established in 1982
- Biotechnology companies established in 1982
- Companies formerly listed on the Nasdaq
- Pharmaceutical companies established in 1982
- Gilead Sciences
- Pharmaceutical companies of the United States
- Biotechnology companies of the United States
- Morris Plains, New Jersey
- Companies based in Morris County, New Jersey
- Biopharmaceutical companies
- Pharmaceutical companies based in New Jersey
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