Английская Википедия:Isocomene

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Isocomene is a sesquiterpene first isolated from the perennial herb southern goldenbush (Isocoma wrightii),[1] from which it derives its name. Its unusual structure consisting of three fused cyclopentane rings was first described by Zalkow et al. in 1977.[1] The first total synthesis of isocomene was published by M.C. Pirrung in 1979.[2] The key steps are a photocatalyzed intramolecular [2 + 2] cycloaddition reaction followed by a rearrangement reaction which forms three contiguous chiral centers.[3]

References

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